Posted on September 24, 2020 by iwano@_84
LA JOLLA–Your lungs and airways need to be stretchy, sort of like balloons. Take a big breath, and they’ll open right up.
Damaged lungs can’t open properly. Patients with asthma, idiopathic pulmonary fibrosis and systemic sclerosis suffer from fibrosis and tissue remodeling, where a build-up of tissue and immune cells, and proteins that form a glue-like substance, keep the airways from expanding. As fibrosis gets worse, taking a breath feels like blowing up a balloon filled with concrete.
In a new study, researchers at La Jolla Institute for Immunology (LJI) report that a protein called TL1A drives fibrosis in several mouse models, triggering tissue remodeling, and making it harder for lungs and airways to function normally.
“Our new study suggests that
Posted on September 23, 2020 by iwano@_84
Two years after the Pentagon set out to spend billions on 10 breakthrough research and engineering efforts, defense contractors instead are putting most of their money in less ambitious research projects. The development gap between the military and its suppliers troubled investigators at the Government Accountability Office, or GAO, who determined in a report released Thursday that the Defense Department isn’t keeping good watch over those private efforts and doesn’t know how much of it would fit into the military’s tech goals.
The Pentagon’s undersecretary for research and engineering in 2018 laid out several big idea research areas that would be most relevant to maintaining an edge on China or Russia. Many are in the very early stages of maturation; the biggest breakthroughs are expected in the second half of the coming decade.
They are: artificial intelligence, autonomy, biotechnology, directed energy, space, cyber, microelectronics, hypersonics, networked command and control, and
Posted on May 5, 2020 by iwano@_84
When it comes to investment property renovations the question I always get asked is – “how much work should I do”? The answer to this question will change dramatically depending on each person and their current situation. Are you the kind of person that loves DIY (do it yourself) home renovations? Do you love researching cheap renovation ideas? Or does the thought of a month’s DIY home renovation make you feel sick? Only you can answer these questions but believe me there are huge advantages of doing minor renovations let alone a full month’s work on a property
So let’s assume that you have 2-5 weeks to complete your DIY renovations, what is a realistic goal to try and achieve? To a certain extent this will depend on your budget but you would be surprised at how much you can get done if you find some good cheap renovation ideas. … Read More
Posted on May 5, 2020 by iwano@_84
Bathrooms are one of the smallest rooms in the house and they are also one the most costly to renovate. Bathroom renovation is a job that, if done well, can add value to a home and a great space full of design and light.
Bathroom design is the first area of your bathroom renovation you need to get right. Just replacing the existing bathroom with the same design may not be enough. The key to great bathroom design is to design it with the people that are going to use it in mind. However be sure that your bathroom design also has a general use factor as well. For example: If you were designing a bathroom for families you could still design the bathroom with easy access to the shower and bath. This would ensure that the design would also work for people with limited mobility. This means … Read More
Posted on May 4, 2020 by iwano@_84
If your kitchen isn’t living up to your expectations, give it a makeover for convenience and pizazz using the steps below.
Posted on May 2, 2020 by iwano@_84
Step 1 – The Study of Space:
Space – How much can I have? The next step is to find out more about the space that is available for this new bathroom. Is it restricted to the existing bathroom footprint? Can you remove the linen closet and use that space in a different way? Do you really use the whirlpool tub? Can you use an adjacent closet, a coat closet or part of the adjacent bedroom? Empty nesters may be very willing to give up a bedroom to make a new master bath. Master baths with all the amenities can take up a lot of space in a hurry. Look at all the options. Be creative and think outside the “box”.
Now look at the room(s) available. Are there windows that will dictate the design? Is there a finished or unfinished basement below? Is there a crawl space below? How … Read More