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Tag: Step

A step toward helping patients breathe deeply

IMAGE

IMAGE: A protein called TL1A drives fibrosis in several mouse models, making it harder for lungs and airways to function normally.
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Credit: La Jolla Institute for Immunology

LA JOLLA–Your lungs and airways need to be stretchy, sort of like balloons. Take a big breath, and they’ll open right up.

Damaged lungs can’t open properly. Patients with asthma, idiopathic pulmonary fibrosis and systemic sclerosis suffer from fibrosis and tissue remodeling, where a build-up of tissue and immune cells, and proteins that form a glue-like substance, keep the airways from expanding. As fibrosis gets worse, taking a breath feels like blowing up a balloon filled with concrete.

In a new study, researchers at La Jolla Institute for Immunology (LJI) report that a protein called TL1A drives fibrosis in several mouse models, triggering tissue remodeling, and making it harder for lungs and airways to function normally.

“Our new study suggests that

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Pentagon, Defense Contractors Are Out Of Step On Tech Innovation, GAO Finds

Two years after the Pentagon set out to spend billions on 10 breakthrough research and engineering efforts, defense contractors instead are putting most of their money in less ambitious research projects. The development gap between the military and its suppliers troubled investigators at the Government Accountability Office, or GAO, who determined in a report released Thursday that the Defense Department isn’t keeping good watch over those private efforts and doesn’t know how much of it would fit into the military’s tech goals.

The Pentagon’s undersecretary for research and engineering in 2018 laid out several big idea research areas that would be most relevant to maintaining an edge on China or Russia. Many are in the very early stages of maturation; the biggest breakthroughs are expected in the second half of the coming decade. 

They are: artificial intelligence, autonomy, biotechnology, directed energy, space, cyber, microelectronics, hypersonics, networked command and control, and

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DIY Home Renovation Tips – A Step by Step Guide to Home Renovations

When it comes to investment property renovations the question I always get asked is – “how much work should I do”? The answer to this question will change dramatically depending on each person and their current situation. Are you the kind of person that loves DIY (do it yourself) home renovations? Do you love researching cheap renovation ideas? Or does the thought of a month’s DIY home renovation make you feel sick? Only you can answer these questions but believe me there are huge advantages of doing minor renovations let alone a full month’s work on a property

So let’s assume that you have 2-5 weeks to complete your DIY renovations, what is a realistic goal to try and achieve? To a certain extent this will depend on your budget but you would be surprised at how much you can get done if you find some good cheap renovation ideas. … Read More

Bathroom Renovation – A Step by Step Guide

Bathrooms are one of the smallest rooms in the house and they are also one the most costly to renovate. Bathroom renovation is a job that, if done well, can add value to a home and a great space full of design and light.

Bathroom design

Bathroom design is the first area of your bathroom renovation you need to get right. Just replacing the existing bathroom with the same design may not be enough. The key to great bathroom design is to design it with the people that are going to use it in mind. However be sure that your bathroom design also has a general use factor as well. For example: If you were designing a bathroom for families you could still design the bathroom with easy access to the shower and bath. This would ensure that the design would also work for people with limited mobility. This means … Read More

Decluttering Blueprint – Step 3 – Organizing Your Kitchen

If your kitchen isn’t living up to your expectations, give it a makeover for convenience and pizazz using the steps below.

  1. Take stock of your kitchens purpose. Is it for cooking, baking, eating, and storing food? If so, move all the items that are unrelated to the purpose of your space (such as papers, magazines, tools, etc.) to other, more appropriate rooms of your home.
  2. Identify the major categories of items to be kept in your kitchen. For example:
  • Cookware – skillets, saucepans, stew pots, and lids.
  • Bakeware – cookie sheets, pie pans, cake pans, and muffin pans.
  • Appliances – coffee maker, toaster, food processor, bread machine, and mixer.
  • Kitchen tools – vegetable peeler, egg slicer, thermometer, cork screw, manual can opener, box grater, cutting board, rolling pin, strainer, and sifter.
  • Utensils – spoons, forks, spatulas, tongs, whisks, pastry brush, and grilling utensils.
  • Dinnerware, glassware and flatware – plates, bowls,
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Design Your Bathroom Using a Six Step Process

Step 1 – The Study of Space:

Space – How much can I have? The next step is to find out more about the space that is available for this new bathroom. Is it restricted to the existing bathroom footprint? Can you remove the linen closet and use that space in a different way? Do you really use the whirlpool tub? Can you use an adjacent closet, a coat closet or part of the adjacent bedroom? Empty nesters may be very willing to give up a bedroom to make a new master bath. Master baths with all the amenities can take up a lot of space in a hurry. Look at all the options. Be creative and think outside the “box”.

Now look at the room(s) available. Are there windows that will dictate the design? Is there a finished or unfinished basement below? Is there a crawl space below? How … Read More